Ergothioneine

What is ergothioneine

Ergothioneine (L-Ergothioneine, EGT, ERGO) is a natural and rare chiral amino acid strong antioxidant. It was first discovered in ergot fungi in 1909. It is a natural antioxidant, safe and non-toxic, and has the functions of detoxification and maintenance. DNA biosynthesis and other physiological functions. Ergothioneine is a natural sun shield, which can block ultraviolet rays from damaging the skin. It can also repair damaged collagen and elastic fibers, shrink pores, and act as sunscreen. It can also effectively remove high-concentration free radicals in the human body and remove stains. , whiten skin, delay aging and prevent various diseases. Antioxidation is mainly reflected in slowing down the aging rate of the human body, which is also the core function of ergothioneine. However, since the human body cannot synthesize ergothioneine on its own, it must be obtained from the outside world.

Efficacy of ergothioneine

1. Antioxidant effect of ergothioneine

Ergothioneine is a natural antioxidant. Its special physical and chemical properties and specific distribution make its stability significantly better than common antioxidants. Its antioxidant properties can be compared with commonly recognized antioxidants such as glutathione (GSH) and ascorbic acid. Comparable to oxidants. The strong antioxidant properties of ergothioneine can be exerted through a variety of mechanisms through its powerful free radical scavenging ability. The antioxidant properties in vitro are also reflected in its interaction with light free radicals (·0H), hypochlorite, singlet oxygen and peroxides. The free electron binding of oxynitrite and its high redox potential make it an effective antioxidant by quenching singlet oxygen and scavenging ·0H. Ergothioneine can also activate antioxidant enzymes that can scavenge reactive oxygen species (ROS), such as glutathione peroxidase (GSH-Px) and superoxide dismutase (Superoxide Dismutase, SOD). , thereby exerting antioxidant effect

2. Anti-inflammatory effect of ergothioneine

The inflammatory response in the body is a common defensive natural response to stimuli, and it is also a manifestation of the body's fight against damaging factors. Studies have found that ergothioneine has a significant inhibitory effect on the activation of nuclear factor-kB (NF-kB) and the release of interleukin-8 (IL-8) in human alveolar epithelial cells. In addition, ergothioneine's inhibitory effect on peroxynitrite anion-mediated amino acid oxidation (such as tyrosine nitration) also provides a feasible therapeutic reference for the treatment of inflammation.

3. The protective effect of ergothioneine on ultraviolet rays and Y-rays

The protective effect of ergothioneine on ultraviolet and Y-rays. Excessive ultraviolet (UV) radiation can cause the skin to produce excessive ROS, accelerate the division and proliferation of epidermal cells, degrade the extracellular matrix and reduce the synthesis of collagen fibers; making the skin rough. Looseness and pigmentation can lead to skin oxidation and inflammatory damage, and even skin cancer. Ergothioneine at physiological concentrations not only protects against UV damage, but also acts as an anti-inflammatory agent in chronic inflammatory diseases. Therefore, ergothioneine can serve as an effective protector against inflammatory damage induced by UVB radiation. one.

4. Color-protecting effect of ergothioneine

The extent of myoglobin and lipid peroxidation in foods, especially meat, correlates with color changes. Antioxidants such as glutathione and ascorbic acid are often used to stabilize the color of meat and are oxidized. Ergothioneine can restore these endogenous antioxidants and ensure the color stability of fish, livestock and poultry meat through a cooperative pathway, thereby playing a role in The function of preserving freshness and protecting color. Ergothioneine extracted from Pleurotus eryngii can protect the color of stored fish meat, and its concentration is directly proportional to the color-protecting effect. Studies have found that ergothioneine can significantly inhibit the blackening of Penaeus vannamei, which is of great significance for the application of ergothioneine in the food field to extend the shelf life and storage time of food and improve the eating quality. Compared with currently common synthetic preservatives, ergothioneine is natural, non-toxic, highly safe to use, can exert better preservation effects and better color protection effects, and is also effective against protein oxidation and rancidity. inhibitory effect.

5. The regulatory effect of ergothioneine on cellular energy

The role of ergothioneine in promoting platelet respiration and regulating cellular energy is similar to the role of carnitine in the process of acyl-CoA derivatives crossing the mitochondrial membrane. There are no mitochondria in red blood cells, so they can only use the pentose phosphate branch to complete their own energy supply and generate lactic acid. Ergothioneine can increase the activity of phosphofructokinase, thus promoting the energy supply to cells. Ergothioneine can meet the energy needs of various physiological activities of the mushroom after harvest, maintain the energy charge at a high level, ensure the normal metabolic function of the organism and the structural function of the membrane system, and delay the browning of the mushroom after harvest. and aging, closely related to intracellular energy metabolism

Why choose us

• Xi'an Xinlu Biotechnology is a professional manufacturer and supplier of ergothioneine.

• Our GMP-certified factory ensures the production of high-quality ergothioneine with a substantial inventory.

• We offer OEM services to meet your specific needs, and our efficient delivery system ensures prompt receipt of your orders.

• Our products are securely packaged and undergo rigorous testing to guarantee their quality and purity.

Our Certificate

We are certified by GMP, KOSHER, HALAL, HACCP and ISO

Our Factory

Xinlubio is a leading professional company dedicated to pure and natural products since 2013. Xinlubio is a professional supplier, we pursue high quality products. We hope to establish a long-term cooperative relationship with every customer

Package

1kg aluminum foil bag or 25kg Drum

FAQ

1. What we do

We are a botanical extract manufacturer, which means we do customized products. So if you cannot find ready products here, you can email us detailed requirement and we'll try our best to tailor the suitable product for you. Even if we are not able to supply you, we'll let you know asap too.

2.What file do you need to prepare if you want to get a quotation from us Please tell us some info.

about what you need, like quantity, destination, application, your company name and contact info.etc.

If you bought it before, It's better that you have a exist spec. for us. Off course more details it will be helpful for us to reccomend a suitable product for you.

3. How about the delivery

Normally, for sample order, our delivery is about 2-4 days.

For small batch, our delivery is about 3-5 days.

For mass production batch, our delivery is about 4-8 days.

But that depends on the real condition when we get your order.

4.How can we guarantee you receive a good quality product

Our management is in this feild over 15 years and our facotry is GMP and ISO certified.

we use advanced philosophy and equipment.

5. With payment terms do we accept

For sample orders or small batch, we suggest you to use Pay-pal and Western Union.For mass production batch, we suggest you to use T/T.

6.With transportation do we use

For small quantity, it will be sent to you by DHL and EMS etc.

For mass production batch, it will be delivered by air or sea.

Contact us

lf you are looking for a reliable source of this valuable compound, please do not hesitate to contact us at xinlubio@vip.163.com..